Planning a short jaunt to ‘Frisco? I’ve got you covered with this step-by-step guide to planning the perfect 48 hours in San Francisco. Your awesome San Francisco itinerary for two days.

An amazing San Francisco travel itinerary packed with things to do in your San Francisco trip. #travel #california #thediscoveriesof

Heading to San Francisco? Are you excited?

I guarantee that you are not excited enough…

Of all the major US cities that I’ve visited, I have to say San Fran is my personal favourite. A city that lives up to the (huge) amount of hype, it’s the perfect destination for a short trip.

Two days in a big city is a tough gig – there’s so much to do and see that it can be overwhelming.

No fear – this step-by-step guide to spending 48 hours in San Francisco, created in partnership with Expedia.com, will have you planning the perfect trip in no time.

For places to stay, visit Expedia.com San Francisco hotels.

Travelling to the West Coast of the USA? You should also read…

48 Hours in San Francisco: At a Glance

  • Go Shopping in Union Square
  • Hang out in Chinatown
  • Walk in the Footsteps of the Beat Poets at City Lights Bookstore
  • Feast in the Ferry Building
  • Escape from Alcatraz
  • Spot the Sea Lions on Pier 39
  • Climb the Filbert Street Steps to Coit Tower for Spectacular Views
  • Cocktails at Bourbon & Branch
  • Check out the Street Art in Balmy Alley
  • Hike Through Golden Gate Park to Golden Gate Bridge
  • Swing by the Painted Ladies – The Colourful Houses near Alamo Square
  • Get a Burrito at La Taqueria in The Mission
  • Catch a flick at the Castro Theater
San Francisco Bay. An amazing San Francisco travel itinerary packed with things to do in your San Francisco trip. #travel #california #thediscoveriesof
Views of the Bay

San Francisco Itinerary 2 Days: Day One

So it’s day one of your 48 hours in San Francisco, you’re fresh and raring to go… or at least I hope you are.

Put on some comfortable walking shoes, you’re going to need them.

Things to see in San Francisco in 2 Days: Day One

Go Shopping in Union Square

Whether you’re a shopping person or not, you can’t visit San Francisco without swinging by its pulsing heart, Union Square. It’s the perfect spot to start your 2 days in San Francisco itinerary.

The square takes its name from the Thomas Starr King rallies that took place here during the Civil War, but these days it’s all about the bright lights and the big shops.

Union Square is kind of what Times Square is to New York,  but a little more low-key. It’s also home to Macy’s, Bloomingdale’s and Saks Fifth Avenue… just don’t spend all your money at once.

Hang out in Chinatown

Chinatown is (along with The Mission and Castro) totally one of my favourite neighbourhoods in San Francisco.

While it’s ensconced between North Beach, Union Square and Nob Hill, a walk through Chinatown is like walking through a completely different city.

It’s the oldest Chinatown in the USA – be sure to stop off at the Golden Gate Bakery for some stellar egg custard tarts, or pop into the Golden Gate Cookie Factory for a peek (and a taste) at how fortune cookies are made.

Walk in the Footsteps of the Beat Poets at City Lights Bookstore

Who are the Beat Poets? Do the names Allen Ginsberg, Jack Kerouac, Philip Whalen or William S. Burroughs mean anything to you? I bet they do.

The Beat Poets or Beat Writers embodied a literary movement that rejected the standards of the American Dream in favour of a more eclectic, experimental and (ahem) sexual life.

Whether you love them or hate them (personally, I’m not a fan of Kerouac’s’ work – Big Sur’s kind of cool but On the Road is grating), you should head to City Lights Books. It was one of the poets’ hangouts and still a landmark indie bookstore today.  

Feast in the Ferry Building

Not sure what you want to eat? Head to the Ferry Building.

Ferry Building. 2 fun-filled days in San Francisco! Get your comfortable shoes on and lets explore the best things to do in San Francisco during a city break. #travel #california #thediscoveriesof
The Ferry Building

A tri-weekly Farmer’s Market (on Tuesday, Thursday and Saturday mornings and early afternoon – hopefully one of them coincides with your 2 day trip in San Francisco) and a host of small restaurants and eateries are guaranteed to tempt you.

I’ll confess that I LOVE oysters, so I can never resist popping into the Hog Island Oyster Company and gorging on their super-fresh raw oysters (washed down with a glass of crisp white of course).

However, there are plenty of other options to choose from in the Ferry Building if that sounds like your idea of hell.

Climb the Filbert Street Steps to Coit Tower for Spectacular Views

Remember when I told you to wear those comfortable walking shoes for this San Francisco two day itinerary? I hope you had a hearty lunch because you’re going to need all the energy you can get.

Coit Tower. 2 fun-filled days in San Francisco! Get your comfortable shoes on and lets explore the best things to do in San Francisco during a city break. #travel #california #thediscoveriesof
Coit Tower

Climbing the Filbert Street Steps to Coit Tower can feel like a never-ending task. Your quads will ache and at some point you’ll wonder whether it’s all worth it.

It is – the views from Coit Tower are some of the best in the city.

Don’t forget to look back as you slog your way up either, practically each step comes with a better photo-opp.

Escape from Alcatraz

Alcatraz, the infamous prison on the rock. So many films have been made about it and set on it (Murder in the First is a personal fave) that it has one hell of a reputation.

Alcatraz Prison. 2 fun-filled days in San Francisco! Get your comfortable shoes on and lets explore the best things to do in San Francisco during a city break. #travel #california #thediscoveriesof

Alcatraz was a maximum-security prison. Impossible to get out of alive, but ridiculously expensive to maintain – the reason why it closed in 1963 and became a national park.

Hop on the ferry from Pier 33: the views of the the bay would be worth the journey alone.

Spot the Sea Lions on Pier 39

Sea lions in the heart of the city? Why not? The sea lions have been hanging out on Pier 39 for as long as anyone can remember.

It’s a short walk from the pier where you return from Alcatraz and the cute picture opportunities are too good to pass up.

Cocktails at Bourbon & Branch

Yeah, it’s very much on the tourist radar, but this Prohibition-Style cocktail bar is still one of the best places to transport yourself to the 1920s with an expertly-made cocktail or two (or three).

Bourbon & Branch has a few house rules – no mobile phones, no cosmos and you need to “speak easy”…

In other words, tone it down on the volume side, as one of my rather irritating exes once told me when we popped in there one evening. Still bitter about that experience but the cocktails are great.

San Francisco Itinerary 2 Days: Day Two

Things to see in San Francisco in 2 Days: Day Two

Hike Through Golden Gate Park to Golden Gate Bridge

London has Big Ben, New York has The Statue of Liberty and San Francisco has the Golden Gate Bridge.

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There’s no way that I could talk about seeing San Francisco in 2 days and not include a trip to the Golden Gate Bridge.

Now, I’ll level with you. You can easily get to the bridge using public transport… but where’s the fun in that?

The Golden Gate Park is the city’s green lung – a patchwork of wooded areas and wide-open spaces offering tantalising glimpses of the bridge before you finally arrive.

You might want to catch a bus back into town though, it’s about an hour and a half walk to our next stop..

Swing by the Painted Ladies – The Colourful Houses near Alamo Square

You know all those pictures you’ve seen of San Francisco’s ridiculously pretty and colourful houses?

Let me introduce you to The Painted Ladies.

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The Painted Ladies looking GREAT

Decorated in an array of gorgeous colours, the ladies are one of the iconic San Fran photo opps.

Don’t forget to take about a million pictures. Have you really seen somewhere if you haven’t put it on the ‘Gram to prove it? Exactly.

Get a Burrito at La Taqueria in The Mission

Well done. The second morning of this 48 hours in San Francisco itinerary is pretty full on. You’ll be happy to hear that a) you’ve made it to lunch and b) it’s plain sailing from here.

Mmmmn burritos. You think you’ve had good burritos. Scrap that, you think that you have had great burritos before. And then you go to La Taqueria.

OMG, the burritos here are insane. Bursting with flavour, packed with tasty, tasty filling and big. Big is good.

Check out the Street Art in Balmy Alley

Hands up if you love street art? I totally do.

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Colorful street art in Balmy Alley

Urban murals, street art, pretty graffiti – whatever you want to call it, Balmy Alley in the lively Mission District is the place to go and see it street art in San Francisco.

Balmy Alley might only be a block long but it’s a walk through the various artists’ damning political statements, joys and frustrations – there’s nowhere else quite like it.

Catch a flick at the Castro Theater

I normally wouldn’t tell you to go to the cinema when you are only in town for two days. I mean, you can totally watch the latest mega-action blockbuster in your hometown right? Right.

Castro Theatre. An amazing San Francisco travel itinerary packed with things to do in your San Francisco trip. #travel #california #thediscoveriesof
Castro Theatre

What you can’t do is go to a sing-a-long movie screening in a Spanish colonial baroque inspired theater in the heart of the Castro, San Fran’s poppin’ LGBT neighbourhood.

Book your tickets to the Castro Theater ahead. You won’t want to miss this.

What is the Best Way to See San Francisco in 2 Days

San Francisco is pretty easy to walk around (beware the hills though), so I’d say the best way to see San Francisco in 2 days is to just walk.

Buuut, you also have to take a trolley car at some point – it’s pretty much mandatory. And it will save your calves some serious burn.

Should I Tour San Francisco in 2 Days?

If you don’t want to walk this itinerary, you can jump on the hop-on-hop-off bus tour to most of the destinations mentioned.  

Where to Stay to See San Francisco in 2 Days

Like all big cities, San Francisco has a lot of options when it comes to accommodation and areas to bed down for the night.

Inside Alcatraz Prison. An amazing San Francisco travel itinerary packed with things to do in your San Francisco trip. #travel #california #thediscoveriesof
Alcatraz isn’t one of them thankfully

I’ve chosen a few different districts that would work for this itinerary, with hotel recommendations for each one.

Union Square / Downtown

Union Square is right in the thick of the action.

Buzzing nightlife, lots of shops and great transportation links make this a great option for a short stay. Plus some of the city’s best restaurants and bars are in this area, so it’s a short distance to roll yourself home if you overindulge.

Suggested Stay: Hotel Zeppelin

Fisherman’s Wharf

Again, it’s touristy and prices are relatively high, but Fisherman’s Wharf is a great place to base yourself if you’re only in San Francisco for a couple of days. It’s central, not on a hill (!) and it’s easy to get to most areas of the city on foot or using public transport.

Suggested Stay: Argonaut Hotel

Haight Ashbury

You might not bag a spot in the pretty Painted Ladies, but Haight Ashbury is a hub of hipster coffee shops, boutique shops and laid-back hangouts.

It’s also one of the best parts of town for accessing the Golden Gate Park nice and early on day two of your San Francisco 2 day trip.

On the minus side, it is HILLY and it’s not so centrally located for walking to other parts of San Fran.

Suggested Stay: The Red Victorian

The Mission

The Mission might not be the most obvious area to stay in San Francisco, but it’s certainly one of the liveliest.

With a heavy Latin-American influence, it’s packed with trendy (and not so trendy) bars, restaurants and taquerias.

Not to mention some of the best street art in town.

Suggested Stay: Noe’s Bed & Breakfast

What to Pack for 48 Hours in San Francisco

Essential items that you need to pack for your 2 day trip in San Francisco.

San Francisco 2 Days Itinerary Map

Need to Know: Practical Information for Your San Francisco 2 Day Trip

How to get to San Francisco

You can fly direct to San Francisco from a number of national and international destinations. If flights are expensive, it’s worth checking whether it’s cheaper to fly to Oakland, which is only on the other side of the bay and easily accessible via public transport.

Read More USA Travel Guides and Tips

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This post was created in partnership with Expedia.com. I’m sure you can tell but all opinions within this article are very much my own.

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